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Mechanism of Action# Preclinical mechanism -- The following description is based on cell culture and animal studies

Pharmacological Reviews, 59(2), 151184

This initial response reflects the peptides modulation of inflammatory pathways rather than actual tissue regeneration, which takes longer to manifest

Study on the quaternary structure suggested that rhGPx3 mutant existed as a monomer in solution, which is different from native tetrameric GPx3

The protective effect of vitamin E seen in this study was enhanced by the addition of the antioxidant vitamin C (Thamilselvan 2014)